Psoriasis is a long-lasting autoimmune disease, characterised by patches of abnormal skin. These skin patches are typically itchy, red and scaly. Psoriasis varies in severity from small, localised patches, to complete body coverage. It is a distressing condition.
There is a range of approaches we can use at The Dove Clinic, due to our interest in the microbiome. What we do know is that gut microbial composition in patients with Psoriasis is abnormal [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830498/pdf/41598_2018_Article_22125.pdf
We do know that there is a connection between Psoriasis and the microbiota [2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023392/
What we also know is that there is evidence of bacteria in the blood in patients with Psoriasis, as opposed to normals. [3] https://www.ncbi.nlm.nih.gov/pubmed/20607546.
From a treatment point of view, we can work on modifying the gut microbiome, which has an important connection with the skin microbiome. This can be done using diet and nutritional medications, and certain specific probiotics and prebiotics. The majority of Probiotics don’t work.
Anecdotally, we know that some patients with Psoriasis have been helped using Colon Hydrotherapy. What we also know is that there have been some dramatic anecdotal results from the treatment of Psoriasis using Faecal Microbiome Transplantation. These are safe treatments, and what we do know is that treating the gut microbiome with Faecal Microbiome Transplantation is effective in autoimmune disease.
References:
- Gut microbial composition in patients with psoriasis Francisco M. Codoñer1, Ana Ramírez-Bosca2,3, Eric Climent1, Miguel Carrión-Gutierrez4, Mariano Guerrero2, Jose Manuel Pérez-Orquín5, José Horga de la Parte6, Salvador Genovés7, Daniel Ramón1,7, Vicente Navarro-López2,8 & Empar Chenoll 7 Scientific ReportS | (2018) 8:3812 | DOI:10.1038/s41598-018-22125-y
2. Psoriasis and Microbiota – a Systematic Review Farida Benhadou,1,* Dillon Mintoff,2 Benjamin Schnebert,3 and Hok Bing Thio4 Diseases. 2018 Jun; 6(2): 47 Published online 2018 Jun 2. doi: 10.3390/diseases6020047
3. Evidence for the presence of bacteria in the blood of psoriasis patients. Munz OH1, Sela S, Baker BS, Griffiths CE, Powles AV, Fry L. Arch Dermatol Res. 2010 Sep;302(7):495-8. doi: 10.1007/s00403-010-1065-0. Epub 2010 Jul 4